Protein Interaction Antibody Pairs
ABclonal Technology Phospho-MDM2-S166 Rabbit mAb
This gene encodes a nuclear-localized E3 ubiquitin ligase The encoded protein can promote tumor formation by targeting tumor suppressor proteins such as p53 for proteasomal degradation This gene is itself transcriptionally-regulated by p53 Overexpression or amplification of this locus is detected in a variety of different cancers There is a pseudogene for this gene on chromosome 2 Alternative splicing results in a multitude of transcript variants many of which may be expressed only in tumor cells
Cayman Chemical mP-9 Q279R VarInthumnr 20ug
Active recombinant C-terminal His-tagged protein expressed in HEK293 cells • Amino acids: 20-707 • MW: 77.8 kDa
Sino Biological Recombinant Human AMPK Protein (full length, His Tag)
Recombinant full-length human AMPK (combination of A2/B2/G3 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags.
Sino Biological Recombinant Human CDK4 Protein (full length, GST Tag)
Recombinant full-length human CDK4 and CyclinD2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.
Sino Biological Recombinant Human CDK4 Protein (full length, GST Tag)
Recombinant full-length human CDK4 and CyclinD2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.
Sino Biological Recombinant Human CUL1/RBX1 Complex Protein (GST Tag)
Recombinant full-length human CUL1 and RBX1 were expressed by baculovirus in Sf9 insect cells using an N-terminal GST tags.
Sino Biological Recombinant Human Her2/ERBB2 Protein (ECD, domain IV, His Tag), Endotoxin-Free
A DNA sequence encoding the human ERBB2 (NP_004439.2) (Pro489-Cys630) was expressed with a polyhistidine tag at the C-terminus.
Sino Biological Recombinant Human Her2/ERBB2 Protein (ECD, domain IV, His Tag), Endotoxin-Free
A DNA sequence encoding the human ERBB2 (NP_004439.2) (Pro489-Cys630) was expressed with a polyhistidine tag at the C-terminus.
ABclonal Technology p-CDK1-T161-CDK2/CDK3-T160
The protein encoded by this gene is a member of the Ser Thr protein kinase family This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF) which is essential for G1 S and G2 M phase transitions of eukaryotic cell cycle Mitotic cyclins stably associate with this protein and function as regulatory subunits The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology Phospho-eIF4EBP1-T70
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology Phospho-eIF4EBP1-T70
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology p-PLC gamma 1 PLCG1-S1248
The protein encoded by this gene catalyzes the formation of inositol 1 4 5-trisphosphate and diacylglycerol from phosphatidylinositol 4 5-bisphosphate This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators For example when activated by SRC the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi where it activates Ras Also this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology Phospho-eIF4EBP1-T37
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology p-CDK1-T161-CDK2/CDK3-T160
The protein encoded by this gene is a member of the Ser Thr protein kinase family This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF) which is essential for G1 S and G2 M phase transitions of eukaryotic cell cycle Mitotic cyclins stably associate with this protein and function as regulatory subunits The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology NCK1 Rabbit pAb
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.